News

Updates from NHS BSA, MHRA drug safety alerts, and other medical news.

MHRA Alert – Prolonged-Release Opioids: Post-Operative Pain Indication Removed

Key Safety Update The MHRA has removed the post-operative pain indication from all prolonged-release opioid medicines. This change reflects growing evidence of the risk of persistent post-operative opioid use (PPOU) and opioid-induced ventilatory impairment in this patient group. What Has Changed Prolonged-release opioid formulations are no longer licensed for the relief of post-operative pain. This […]